Monday, March 9, 2009

Fluorescent screening test for G6PD deficiency

G6PD will produce NADPH from NADP+.These NADPHs will fluoresces under UV light.In G6PD deficiency,less fluoresces occur due to less NADPH production

in what case,the result is false?
  • False normal

Reticulocyte has large amount of G6PD.Therefore a small num of reticulocytes will produce large num of NADPH,

  • False deficient

In anaemic condition,very little fluoresces is seen,eventhough the G6PD IS NORMAL




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